R23 is a trimmer and must be set to maximum resistance (10kOhm) when powering up. Then the resistance of R23 must be decreased until the the quiescent current is achieved. If the amplifier is mounted on a big enough heatsink ( 0.6K/W at most) then the amplifier is very safe from thermal runaway. Intelligence must be used when choosing power and voltage ratings of resistors and capacitors.
